DNLI

Denali Therapeutics Inc.
—

Company Information

Company Name
Denali Therapeutics Inc.
CIK
CIK0001714899
Category
Large accelerated filer
Ticker: Exchange
DNLI: Nasdaq
Fiscal Year End
December 31
Owner Organization
03 Life Sciences
SIC
2836
SIC Description
Biological Products, (No Diagnostic Substances)
Ticker
DNLI

SEC filing data through

Insider Sentiment

Last purchase
—
Last sale
2026-09-04
Shares purchased (TTM)
0
Shares sold (TTM)
71,134
Buy ratio (TTM)0.0%

Institutional Sentiment

As of
2026-06-30
Institutional shares owned
137,534,950
Shares outstanding
187,314,501
Ownership
73.42%
-0.49% Y/Y

Earnings Market Reaction

Filing date
2026-08-06
Price on filing date
—
1-month reaction
-2.95%
3-month reaction
…
Drift continued9/11 (82%)
Faded / reversed2/11 (18%)

Balance Sheet

Values in millions ($)
Line item2026-06-302026-03-312025-12-312025-09-302025-06-302025-03-312024-12-312024-09-302024-06-302024-03-312023-12-312023-09-30Subscriber-only columnSubscriber-only columnSubscriber-only columnSubscriber-only columnSubscriber-only columnTrend
Assets
Nonrelated Party------------7
Related Party------------7
Assets Current
Cash And Cash Equivalents At Carrying Value2023882059114157175917561127148
Marketable Securities Current509600663757758761657746821876907961
Accounts Receivable Net Current4-----------
Inventory Net4-----------
Prepaid Expense And Other Assets Current353533343661323232373034
Assets Current7541,0239018839358798648699289741,0641,143
Marketable Securities Noncurrent2306498257823635944545149108
Property Plant And Equipment Net505252545958555148474648
Finance Lease Right Of Use Asset4748494950504839--0-
Operating Lease Right Of Use Asset171819202122232425252627
Intangible Assets Net Excluding Goodwill3536----------
Other Assets Noncurrent262626252327252651451811
Assets1,1581,2661,1451,0561,1661,2711,3741,4541,5031,5811,1541,237
Liabilities And Stockholders Equity
Other Liabilities Current----------0-
Liabilities Current
Accounts Payable Current124037118111014129-
Employee Related Liabilities Current-9-18128-15108-16
Accrued Liabilities Current7870955779156668-
Contract With Customer Liability Current----------0-
Liabilities Current90110989091921028775837871
Contract With Customer Liability Noncurrent----------0-
Operating Lease Liability Current-10-999-888-7
Operating Lease Liability Noncurrent222527303234373941434547
Finance Lease Liability Noncurrent56666666--0-
Liabilities323340131129139149144136116126123118
Other Liabilities Noncurrent----------00
Stockholders Equity
Preferred Stock Value Outstanding00000000000-
Preferred Stock Value----------00
Common Stock Value Outstanding22222222222-
Additional Paid In Capital3,1433,1053,0632,8462,8202,7912,7652,7352,7052,6732,1452,114
Common Stock Value----------22
Accumulated Other Comprehensive Income Loss Net Of Tax-2-1111226-3-11-1
Retained Earnings Accumulated Deficit-2,308-2,180-2,052-1,923-1,796-1,672-1,539-1,424-1,317-1,218-1,116-997
Stockholders Equity8359261,0149261,0271,1231,2301,3181,3871,4551,0311,118
Liabilities And Stockholders Equity1,1581,2661,1451,0561,1661,2711,3741,4541,5031,5811,1541,237
Preferred Stock Par Or Stated Value Per Share0.010.010.010.010.010.010.010.010.010.010.010.01
Preferred Stock Shares Authorized404040404040404040404040
Preferred Stock Shares Issued000000000000
Preferred Stock Shares Outstanding000000000000
Common Stock Par Or Stated Value Per Share0.010.010.010.010.010.010.010.010.010.010.010.01
Common Stock Shares Authorized400400400400400400400400400400400400
Common Stock Shares Issued160159156147146145144144143143138138
Shares Outstanding160159156147146145144144143143138138

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Denali Therapeutics Inc. (DNLI) — SEC Financial Statements & Analysis

Denali Therapeutics Inc. (DNLI) is a biological products, (no diagnostic substances) company, incorporated in DE. Denali Therapeutics Inc. trades on Nasdaq as: DNLI. Denali Therapeutics Inc. (DNLI)'s most recent SEC filing is a Form 10-Q for the period ended 2026-06-30, filed with the SEC on 2026-08-06. Based on that filing, Denali Therapeutics Inc. carries a market cap of $4.82B, a P/E ratio of -9.42x, a P/B ratio of 5.77x, a P/S ratio of 1336.77x, an enterprise value of $4.62B, and an EV/EBITDA multiple of -8.71x. On profitability, it posts an operating margin of -15058.19%, a net margin of -14191.20%, a Return on Equity (ROE) of -54.93%, a Return on Assets (ROA) of -44.01%, and a Return on Invested Capital (ROIC) of -71.20%. Per share, it reports EPS of $-2.73, diluted EPS of $-2.73, free cash flow per share of $-2.35, and a dividend per share of $0.00. Over the trailing year, it posted revenue growth of -100.00% year-over-year, net income growth of 6.77% year-over-year, and EPS growth of -2.28% year-over-year. On the balance sheet, it maintains a current ratio of 8.37x, a quick ratio of 7.93x, working capital of $663.84M, a debt-to-equity ratio of 0.39x, a debt ratio of 0.28, free cash flow of $-440.21M (TTM), and net debt of $-199.16M. Figures sourced from SEC EDGAR.

Market Cap
$4.82B
P/E TTM
-9.42x
EPS TTM
$-2.73
P/B TTM
5.77x
ROE TTM
-54.93%
ROA TTM
-44.01%
Debt To Equity
0.39x
Free Cash Flow TTM
$-440.21M
Net Revenue TTM Growth 1Y
-100.00%

Data as of 2026-06-30 · Source: SEC EDGAR

Frequently Asked Questions

What industry is Denali Therapeutics Inc. in?

Denali Therapeutics Inc. (DNLI) operates in the Biological Products, (No Diagnostic Substances) industry.

What exchange does DNLI trade on?

Denali Therapeutics Inc. (DNLI) trades on the Nasdaq.

Where is Denali Therapeutics Inc. incorporated?

Denali Therapeutics Inc. is incorporated in DE.

When was Denali Therapeutics Inc. (DNLI)'s most recent SEC filing?

Denali Therapeutics Inc. (DNLI)'s most recent SEC filing is a Form 10-Q for the period ended 2026-06-30, filed with the SEC on 2026-08-06.

What is DNLI's market cap?

Denali Therapeutics Inc. (DNLI) has a market capitalization of $4.82B as of 2026-06-30.

What is DNLI's EPS (earnings per share)?

Denali Therapeutics Inc. (DNLI)'s trailing twelve month EPS is $-2.73 as of 2026-06-30.

What is DNLI's ROE (return on equity)?

Denali Therapeutics Inc. (DNLI)'s trailing twelve month Return on Equity (ROE) is -54.93% as of 2026-06-30.

What is DNLI's ROA (return on assets)?

Denali Therapeutics Inc. (DNLI)'s trailing twelve month Return on Assets (ROA) is -44.01% as of 2026-06-30.

What is DNLI's ROIC (return on invested capital)?

Denali Therapeutics Inc. (DNLI)'s trailing twelve month Return on Invested Capital (ROIC) is -71.20% as of 2026-06-30.

What is DNLI's EV/EBITDA?

Denali Therapeutics Inc. (DNLI)'s trailing twelve month EV/EBITDA is -8.71x as of 2026-06-30.

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