KPTI

Karyopharm Therapeutics Inc.
—

Company Information

Company Name
Karyopharm Therapeutics Inc.
CIK
CIK0001503802
Category
Non-accelerated filer<br>Smaller reporting company
Ticker: Exchange
KPTI: Nasdaq
Fiscal Year End
December 31
Owner Organization
03 Life Sciences
SIC
2834
SIC Description
Pharmaceutical Preparations
Ticker
KPTI

SEC filing data through

Insider Sentiment

Last purchase
2023-09-12
Last sale
2026-09-01
Shares purchased (TTM)
0
Shares sold (TTM)
40,872
Buy ratio (TTM)0.0%

Institutional Sentiment

As of
2026-06-30
Institutional shares owned
19,954,072
Shares outstanding
28,938,000
Ownership
68.95%
+28.14% Y/Y

Earnings Market Reaction

Filing date
2026-08-13
Price on filing date
—
1-month reaction
-10.05%
3-month reaction
…
Drift continued4/11 (36%)
Faded / reversed7/11 (64%)

Balance Sheet

Values in millions ($)
Line item2026-06-302026-03-312025-12-312025-09-302025-06-302025-03-312024-12-312024-09-302024-06-302024-03-312023-12-312023-09-30Subscriber-only columnSubscriber-only columnSubscriber-only columnSubscriber-only columnSubscriber-only columnTrend
Assets Current
Cash And Cash Equivalents At Carrying Value559161383939627385315244
Available For Sale Securities Debt Securities Current100381331466167118139165
Receivables Net Current302326323335313238312738
Inventory Net444455553333
Prepaid Expense And Other Assets Current7998810121515151213
Restricted Cash And Cash Equivalents At Carrying Value--0---000011
Assets Current1061261039098120156185209198234263
Property Plant And Equipment Net000000001111
Operating Lease Right Of Use Asset445555633445
Restricted Cash And Cash Equivalents Noncurrent000000000000
Other Assets000111111111
Assets11113110896105128164189214204240270
Liabilities Current
Accounts Payable Current844536563531
Accrued Liabilities Current797664666357615050556156
Secured Debt Current403221136-0-----
Operating Lease Liability Current111111044333
Other Liabilities Current632222221222
Liabilities Current13411792879990926158656962
Convertible Long Term Notes Payable------0--171171171
Secured Long Term Debt858895849095959494-0-
Operating Lease Liability Noncurrent556666701234
Other Liabilities Noncurrent00111485264311
Liabilities441397401365344334350349346373377370
Stockholders Equity
Preferred Stock Value000000000000
Common Stock Value000000000000
Additional Paid In Capital Common Stock1,5191,5161,4661,3881,3851,3811,3781,3731,3691,3561,3511,346
Accumulated Other Comprehensive Income Loss Net Of Tax000-0-0-0-0-0-1-1-0-1
Retained Earnings Accumulated Deficit-1,849-1,782-1,759-1,657-1,624-1,587-1,563-1,533-1,501-1,524-1,487-1,445
Stockholders Equity-330-266-293-269-239-206-186-160-132-169-136-100
Liabilities And Stockholders Equity11113110896105128164189214204240270
Preferred Stock Par Or Stated Value Per Share0.000.000.000.000.000.000.000.000.000.000.000.00
Preferred Stock Shares Authorized555555555555
Preferred Stock Shares Issued000000000000
Preferred Stock Shares Outstanding000000000000
Common Stock Par Or Stated Value Per Share0.000.000.000.000.000.000.000.000.000.000.000.00
Common Stock Shares Authorized1061065353535353400400400400400
Common Stock Shares Issued232318999888888
Shares Outstanding232318999888888

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Karyopharm Therapeutics Inc. (KPTI) — SEC Financial Statements & Analysis

Karyopharm Therapeutics Inc. (KPTI) is a pharmaceutical preparations company, incorporated in DE. Karyopharm Therapeutics Inc. trades on Nasdaq as: KPTI. Karyopharm Therapeutics Inc. (KPTI)'s most recent SEC filing is a Form 10-Q for the period ended 2026-06-30, filed with the SEC on 2026-08-13. Based on that filing, Karyopharm Therapeutics Inc. carries a market cap of $282.72M, a P/E ratio of -1.26x, a P/B ratio of -0.86x, a P/S ratio of 1.93x, an enterprise value of $352.78M, and an EV/EBITDA multiple of -4.29x. On profitability, it posts a gross margin of 95.89%, an operating margin of -56.17%, a net margin of -153.28%, a Return on Equity (ROE) of 78.98%, and a Return on Assets (ROA) of -207.90%. Per share, it reports EPS of $-7.77, diluted EPS of $-7.77, free cash flow per share of $-2.26, and a dividend per share of $0.00. Over the trailing year, it posted revenue growth of 6.81% year-over-year, net income growth of 81.88% year-over-year, and EPS growth of -45.82% year-over-year. On the balance sheet, it maintains a current ratio of 0.79x, a quick ratio of 0.71x, working capital of $-27.86M, a debt-to-equity ratio of -1.34x, a debt ratio of 3.97, an interest coverage ratio of -2.36x, free cash flow of $-65.35M (TTM), and net debt of $70.06M. Figures sourced from SEC EDGAR.

Market Cap
$282.72M
P/E TTM
-1.26x
EPS TTM
$-7.77
P/B TTM
-0.86x
ROE TTM
78.98%
ROA TTM
-207.90%
Debt To Equity
-1.34x
Free Cash Flow TTM
$-65.35M
Net Revenue TTM Growth 1Y
6.81%

Data as of 2026-06-30 · Source: SEC EDGAR

Frequently Asked Questions

What industry is Karyopharm Therapeutics Inc. in?

Karyopharm Therapeutics Inc. (KPTI) operates in the Pharmaceutical Preparations industry.

What exchange does KPTI trade on?

Karyopharm Therapeutics Inc. (KPTI) trades on the Nasdaq.

Where is Karyopharm Therapeutics Inc. incorporated?

Karyopharm Therapeutics Inc. is incorporated in DE.

When was Karyopharm Therapeutics Inc. (KPTI)'s most recent SEC filing?

Karyopharm Therapeutics Inc. (KPTI)'s most recent SEC filing is a Form 10-Q for the period ended 2026-06-30, filed with the SEC on 2026-08-13.

What is KPTI's market cap?

Karyopharm Therapeutics Inc. (KPTI) has a market capitalization of $282.72M as of 2026-06-30.

What is KPTI's EPS (earnings per share)?

Karyopharm Therapeutics Inc. (KPTI)'s trailing twelve month EPS is $-7.77 as of 2026-06-30.

What is KPTI's ROE (return on equity)?

Karyopharm Therapeutics Inc. (KPTI)'s trailing twelve month Return on Equity (ROE) is 78.98% as of 2026-06-30.

What is KPTI's ROA (return on assets)?

Karyopharm Therapeutics Inc. (KPTI)'s trailing twelve month Return on Assets (ROA) is -207.90% as of 2026-06-30.

What is KPTI's EV/EBITDA?

Karyopharm Therapeutics Inc. (KPTI)'s trailing twelve month EV/EBITDA is -4.29x as of 2026-06-30.

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