LYRA

Lyra Therapeutics, Inc.
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Company Information

Company Name
Lyra Therapeutics, Inc.
CIK
CIK0001327273
Category
Non-accelerated filer<br>Smaller reporting company
Ticker: Exchange
LYRA: OTC
Fiscal Year End
December 31
Owner Organization
08 Industrial Applications and Services
SIC
3841
SIC Description
Surgical & Medical Instruments & Apparatus
Ticker
LYRA

SEC filing data through

Insider Sentiment

Last purchase
2023-11-10
Last sale
2026-01-06
Shares purchased (TTM)
0
Shares sold (TTM)
55,032
Buy ratio (TTM)0.0%

Institutional Sentiment

As of
2026-03-31
Institutional shares owned
104,059
Shares outstanding
1,553,473
Ownership
6.70%
-31.85% Y/Y

Earnings Market Reaction

Filing date
2026-03-31
Price on filing date
—
1-month reaction
44.69%
3-month reaction
38.46%
Drift continued7/12 (58%)
Faded / reversed5/12 (42%)

Balance Sheet

Values in millions ($)
Line item2025-12-312025-09-302025-06-302025-03-312024-12-312024-09-302024-06-302024-03-312023-12-312023-09-302023-06-302023-03-31Subscriber-only columnSubscriber-only columnSubscriber-only columnSubscriber-only columnSubscriber-only columnTrend
Assets Current
Cash And Cash Equivalents At Carrying Value162230324124321622255422
Prepaid Expense And Other Assets Current011223222222
Short Term Investments0---028367180786261
Restricted Cash Current----------0-
Assets Current162331344354698910510511885
Property Plant And Equipment Net111112242112
Operating Lease Right Of Use Asset171818192021214633612
Restricted Cash Noncurrent222222221111
Assets3644535666799514214312112694
Liabilities Current
Other Assets Noncurrent----0--11744
Accounts Payable Current111112533544
Restructuring Reserve Current3334453-----
Accrued Liabilities And Other Liabilities1---3---9---
Operating Lease Liability Current555444455122
Deferred Revenue Current-00001112212
Liabilities Current10911111315191920191414
Operating Lease Liability Noncurrent2527282930313233215-0
Deferred Revenue Noncurrent121212121212121212121313
Liabilities474851525558646453362728
Common Stock Value000000000000
Additional Paid In Capital Common Stock423422422417416414413411401380379331
Retained Earnings Accumulated Deficit-434-427-421-413-405-394-382-334-311-296-281-265
Stockholders Equity-11-4241221317889849966
Liabilities And Stockholders Equity3644535666799514214312112694
Accumulated Other Comprehensive Income Loss Net Of Tax----00-000-0-0-0
Common Stock Par Or Stated Value Per Share0.000.000.000.000.000.000.000.000.000.000.000.00
Common Stock Shares Authorized200200200200200200200200200200200200
Common Stock Shares Issued222111111111
Shares Outstanding222111111111
Preferred Stock Par Or Stated Value Per Share0.000.000.000.000.000.000.000.000.000.000.000.00
Preferred Stock Shares Authorized101010101010101010101010
Preferred Stock Shares Outstanding000000000000
Preferred Stock Shares Issued000000000000

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Recent filings

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Lyra Therapeutics, Inc. (LYRA) — SEC Financial Statements & Analysis

Lyra Therapeutics, Inc. (LYRA) is a surgical & medical instruments & apparatus company, incorporated in DE. Lyra Therapeutics, Inc. trades on OTC as: LYRA. Lyra Therapeutics, Inc. (LYRA)'s most recent SEC filing is a Form 10-K for the period ended 2025-12-31, filed with the SEC on 2026-03-31. Based on its latest SEC filing (Form 10-Q, period ending 2025-12-31), Lyra Therapeutics, Inc. carries a market cap of $4.78M, a P/E ratio of -0.17x, a P/B ratio of -0.45x, a P/S ratio of 12.02x, an enterprise value of $-11.11M, and an EV/EBITDA multiple of 0.36x. On profitability, it posts an operating margin of -7794.47%, a net margin of -7266.08%, a Return on Equity (ROE) of -6594.98%, a Return on Assets (ROA) of -56.45%, and a Return on Invested Capital (ROIC) of -138.46%. Per share, it reports EPS of $-18.62, diluted EPS of $-18.62, free cash flow per share of $-18.65, and a dividend per share of $0.00. Over the trailing year, it posted revenue growth of -74.05% year-over-year, net income growth of -69.05% year-over-year, and EPS growth of -74.05% year-over-year. On the balance sheet, it maintains a current ratio of 1.71x, a quick ratio of 1.67x, working capital of $6.75M, a debt-to-equity ratio of -4.37x, a debt ratio of 1.3, free cash flow of $-28.98M (TTM), and net debt of $-15.89M. Figures sourced from SEC EDGAR.

Market Cap
$4.78M
P/E TTM
-0.17x
EPS TTM
$-18.62
P/B TTM
-0.45x
ROE TTM
-6594.98%
ROA TTM
-56.45%
Debt To Equity
-4.37x
Free Cash Flow TTM
$-28.98M
Net Revenue TTM Growth 1Y
-74.05%

Data as of 2025-12-31 · Source: SEC EDGAR

Frequently Asked Questions

What industry is Lyra Therapeutics, Inc. in?

Lyra Therapeutics, Inc. (LYRA) operates in the Surgical & Medical Instruments & Apparatus industry.

What exchange does LYRA trade on?

Lyra Therapeutics, Inc. (LYRA) trades on the OTC.

Where is Lyra Therapeutics, Inc. incorporated?

Lyra Therapeutics, Inc. is incorporated in DE.

When was Lyra Therapeutics, Inc. (LYRA)'s most recent SEC filing?

Lyra Therapeutics, Inc. (LYRA)'s most recent SEC filing is a Form 10-K for the period ended 2025-12-31, filed with the SEC on 2026-03-31.

What is LYRA's market cap?

Lyra Therapeutics, Inc. (LYRA) has a market capitalization of $4.78M as of 2025-12-31.

What is LYRA's EPS (earnings per share)?

Lyra Therapeutics, Inc. (LYRA)'s trailing twelve month EPS is $-18.62 as of 2025-12-31.

What is LYRA's ROE (return on equity)?

Lyra Therapeutics, Inc. (LYRA)'s trailing twelve month Return on Equity (ROE) is -6594.98% as of 2025-12-31.

What is LYRA's ROA (return on assets)?

Lyra Therapeutics, Inc. (LYRA)'s trailing twelve month Return on Assets (ROA) is -56.45% as of 2025-12-31.

What is LYRA's ROIC (return on invested capital)?

Lyra Therapeutics, Inc. (LYRA)'s trailing twelve month Return on Invested Capital (ROIC) is -138.46% as of 2024-03-31.

What is LYRA's EV/EBITDA?

Lyra Therapeutics, Inc. (LYRA)'s trailing twelve month EV/EBITDA is 0.36x as of 2025-12-31.

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