Prime Medicine, Inc.

PRME

Prime Medicine, Inc.

PRME

Insider Sentiment (TTM):

Last Purchase:2025-08-01Last Sale:2023-06-21Shares Purchased (TTM):0Shares Sold (TTM):0

Institutional Sentiment:

As of:2026-03-31Institutional Shares Owned:90,065,815Shares Outstanding:177,096,225Institutional Ownership Pct.:50.86%

Earnings Market Reaction:

Filing Date:2026-08-06Price on Filing Date:N/APrevious Close:N/A% Change:N/A

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Financial Statements

10‑Q10‑K

Values in Millions ($)	2026-06-30	2026-03-31	2025-12-31	2025-09-30	2025-06-30	2025-03-31	2024-12-31	2024-09-30	2024-06-30	2024-03-31	2023-12-31	2023-09-30
Nonrelated Party	-	-	115	92	-4	48	3	-50	-7	110	75	36
Related Party	-	-	115	92	-4	48	3	-50	-7	110	75	36
Assets
Assets Current
Cash And Cash Equivalents At Carrying Value	47	64	63	71	54	92	182	118	56	94	42	44
Prepaid Expense And Other Assets Current	-	-	-	-	-	-	-	-	-	-	-	19
Accounts Receivable Gross Current	-	-	-	-	0	0	-	55	-	-	-	-
Available For Sale Securities Debt Securities Curr…	48	71	-	-	-	-	-	-	-	-	-	-
Prepaid Expense Current	1	2	3	2	3	3	7	6	4	4	19	-
Other Assets Current	0	0	1	16	16	17	15	10	4	3	2	-
Assets Current	97	138	181	231	121	164	212	246	171	218	143	185
Property Plant And Equipment Net	17	19	21	22	24	25	24	23	24	24	23	22
Operating Lease Right Of Use Asset	120	123	126	118	120	125	47	49	52	56	14	17
Restricted Cash Noncurrent	14	14	14	14	14	14	14	14	13	13	13	13
Other Assets Noncurrent	1	1	1	-	-	-	0	0	0	1	1	2
Assets	249	295	343	385	279	328	298	333	260	311	194	239
Liabilities And Stockhold…
Liabilities Current
Accounts Payable Current	6	12	9	9	6	10	11	5	5	10	20	14
Accrued Liabilities Current	9	8	13	11	12	9	16	19	11	8	14	14
Contract With Customer Liability Current	8	7	8	7	8	8	7	9	-	-	0	-
Operating Lease Liability Current	9	9	8	8	7	7	4	4	5	7	9	11
Liabilities Current	32	36	37	35	34	34	38	38	21	24	56	39
Contract With Customer Liability Noncurrent	56	58	58	60	60	61	63	63	-	-	0	-
Operating Lease Liability Noncurrent	104	106	108	110	112	114	37	37	36	37	4	6
Deferred Income Tax Liabilities Net	-	-	-	-	-	-	-	-	-	0	0	0
Liabilities	209	218	222	223	218	221	144	143	63	68	61	45
Stockholders Equity
Common Stock Value	0	0	0	0	0	0	0	0	0	0	0	0
Additional Paid In Capital	1,019	1,014	1,009	1,004	853	846	840	834	789	781	624	620
Accumulated Other Comprehensive Income Loss Net Of…	-0	-0	0	0	-0	-0	0	0	-0	-0	-0	-0
Retained Earnings Accumulated Deficit	-980	-937	-888	-842	-792	-739	-687	-645	-592	-537	-491	-426
Stockholders Equity	40	77	121	162	61	107	153	190	197	244	133	194
Liabilities And Stockholders Equity	249	295	343	385	279	328	298	333	260	311	194	239
Common Stock Par Or Stated Value Per Share	0	0	0	0	0	0	0	0	0	0	0	0
Common Stock Shares Authorized	775	775	775	775	775	775	775	775	775	775	775	775
Common Stock Shares Issued	181	181	181	180	134	131	131	131	120	120	97	97
Shares Outstanding	181	181	181	180	134	131	131	131	120	120	97	97

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Earnings Market Reaction

10‑Q10‑K

Fiscal Year	Q1 1 Month	Q1 2 Month	Q1 3 Month	Q2 1 Month	Q2 2 Month	Q2 3 Month	Q3 1 Month	Q3 2 Month	Q3 3 Month	Q4 1 Month	Q4 2 Month	Q4 3 Month
2026	13.96%	10.11%	-5.30%	-	-	-	-	-	-	-	-	-
2025	-10.61%	83.33%	218.94%	-11.96%	39.13%	44.84%	0.26%	-8.14%	16.27%	-20.09%	-12.53%	-29.79%
2024	15.51%	-8.38%	0.00%	-2.51%	-21.18%	-8.20%	-24.31%	-22.45%	-35.19%	-22.62%	-50.79%	-36.90%
2023	-	-	-	1.83%	-23.98%	-55.46%	-6.92%	18.21%	-16.67%	-20.71%	-48.40%	-18.99%
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Performance and Valuation Metrics

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Metrics	2026-06-30	2026-03-31	2025-12-31	2025-09-30	2025-06-30	2025-03-31	2024-12-31	2024-09-30	2024-06-30	2024-03-31	2023-12-31	2023-09-30
Liquidity Ratios
Current Ratio	3.05	3.80	4.84	6.61	3.56	4.78	5.58	6.50	8.23	8.91	2.53	4.69
Quick Ratio	3.01	3.75	4.76	6.54	3.47	4.69	5.40	6.34	8.03	8.73	2.20	4.20
Working Capital	65.11M	101.60M	143.85M	196.39M	87.18M	129.48M	173.93M	208.19M	150.05M	193.21M	86.55M	145.17M
Leverage & Debt
Debt to Equity	5.26	2.84	1.84	1.38	3.58	2.07	0.94	0.76	0.32	0.28	0.46	0.23
Debt Ratio	0.84	0.74	0.65	0.58	0.78	0.67	0.49	0.43	0.24	0.22	0.31	0.19
Efficiency & Turnover
Asset Turnover TTM	0.01	0.01	0.01	0.02	0.02	0.01	0.01	0.00	0.00	0.00	0.00	0.00
Per Share Metrics
Diluted EPS TTM	-1.06	-1.12	-1.35	-1.23	-1.54	-1.54	-1.65	-1.83	-1.82	-1.96	-2.18	-2.60
Free Cash Flow Per Share TTM	-0.93	-0.91	-1.13	-0.41	-0.44	-0.85	-1.10	-1.59	-1.72	-1.92	-1.91	-1.79
Dividend Per Share TTM	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Margin Metrics
Operating Profit Margin TTM	-6,732.44%	-5,121.76%	-4,498.06%	-3,412.48%	-4,116.57%	-5,369.68%	-6,787.36%	-28,286.00%	-37,819.80%	-36,057.53%	-	-
Net Profit Margin TTM	-6,436.86%	-4,917.55%	-4,342.44%	-3,301.64%	-4,016.83%	-5,252.50%	-6,566.61%	-27,406.12%	-36,791.71%	-34,601.86%	-	-
Growth Metrics
Net Revenue Growth (1Y)	-41.16%	4.89%	55.28%	647.13%	739.42%	550.76%	-	-	-	-	-	-
Net Income Growth (1Y)	-5.71%	-1.80%	2.69%	-9.99%	-8.35%	-1.22%	-1.14%	-8.18%	-2.84%	-	-	-
EPS Growth (1Y)	-31.27%	-27.42%	-18.13%	-32.84%	-15.45%	-21.15%	-24.17%	-29.59%	-26.25%	-	-	-
Valuation Metrics
P/E TTM	-3.48	-3.11	-2.57	-4.51	-1.60	-1.29	-1.77	-2.11	-2.82	-3.58	-4.07	-3.67
P/B TTM	16.43	8.04	4.27	5.49	5.24	2.44	2.26	2.45	3.12	3.00	6.06	4.52
P/S TTM	224.04	152.78	111.44	148.77	64.32	67.72	116.10	579.36	1,036.60	1,237.33	-	-
Market Cap	653.96M	616.29M	516.19M	889.19M	319.09M	260.46M	346.31M	463.49M	612.63M	731.26M	805.99M	876.22M
Enterprise Value	606.51M	552.19M	453.16M	817.79M	265.29M	168.58M	149.78M	345.51M	543.53M	623.61M	764.41M	818.76M
Calculated Values
Free Cash Flow TTM	-165.54M	-160.44M	-168.80M	-65.52M	-57.42M	-111.41M	-130.16M	-190.32M	-205.20M	-200.61M	-174.14M	-163.96M
Net Debt	-47.45M	-64.11M	-63.03M	-71.40M	-53.80M	-91.88M	-196.54M	-117.98M	-69.10M	-107.66M	-41.57M	-57.46M
Per-Share and Margin
EPS TTM
Adjusted EPS TTM
Cash Flow Per Share TTM
Pretax Margin TTM
Stock Comp to Revenue TTM
Turnover Ratios and Averages
Average Assets
Average Equity
Average Inventory
Average Receivables
Average Accounts Payables
Inventory Turnover TTM
Payables Turnover TTM
Days Inventory Outstanding TTM
Days Payables Outstanding TTM
Cash Conversion Cycle TTM
Working Capital to Revenue
Deferred Revenue to Revenue
Growth Rates
Total Assets Growth (1Y)
Total Assets Growth (3Y)
Total Assets Growth (5Y)
Dividends Paid Growth (1Y)
Dividends Paid Growth (3Y)
Dividends Paid Growth (5Y)
EPS Growth (3Y)
EPS Growth (5Y)
Net Income Growth (3Y)
Net Income Growth (5Y)
Net Profit Margin Growth (1Y)
Net Profit Margin Growth (3Y)
Net Profit Margin Growth (5Y)
Net Revenue Growth (3Y)
Net Revenue Growth (5Y)
Deferred Revenue Growth (1Y)
Retained Earnings Growth (1Y)
Credit, Liquidity, Returns, Payout
Cash Ratio
Net Working Capital
Debt to EBITDA TTM
Net Debt to EBITDA TTM
Net Debt to Equity
Altman A
Altman B
Altman C
Altman D
Altman E
Altman Z-Score
ROA TTM
ROE TTM
NOPAT TTM
ROIC TTM
Effective Tax Rate TTM
Payout Ratio TTM
Dilution Ratio
Retained Earnings to Equity
Treasury Stock to Equity
Treasury Stock Change (1Y)
Accrued to Current Liabilities
NCAV
NCAV Per Share TTM
Valuation Ratios
P/CF TTM
PEG Ratio
Dividend Yield TTM
Free Cash Flow Yield TTM
EV EBITDA TTM
EV EBIT TTM
EV Revenue TTM
EV FCF TTM
Stock Compensation TTM
Adjusted Net Income TTM
Billings TTM
Total Debt
Invested Capital

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Insider Transactions

2025-08-01Purchase

Owner: Gillis, Steven, Crandell …

Title: -

Shares: 3,030,300

Price/Share: $3.30

Value: $9,999,990.00

Shares Owned: 6,230,300

Relationship: TenPercentOwner

Ownership: Indirect

2025-08-01Purchase

Owner: Nelsen, Robert

Title: -

Shares: 3,030,300

Price/Share: $3.30

Value: $9,999,990.00

Shares Owned: 6,230,300

Relationship: Director,TenPercentOwner

Ownership: Indirect

2025-08-01Purchase

Owner: Alphabet, Inc., Gv 2021, …

Title: -

Shares: 1,500,000

Price/Share: $3.30

Value: $4,950,000.00

Shares Owned: 3,262,440

Relationship: TenPercentOwner

Ownership: Indirect

2025-08-01Purchase

Owner: Arch, Venture Fund Xii, L…

Title: -

Shares: 3,030,300

Price/Share: $3.30

Value: $9,999,990.00

Shares Owned: 6,230,300

Relationship: TenPercentOwner

Ownership: Indirect

2025-06-30Purchase

Owner: Liu, David R.

Title: -

Shares: 21,000

Price/Share: $2.52

Value: $52,920.00

Shares Owned: 20,240,945

Relationship: TenPercentOwner

Ownership: Direct

Filed Date	Owner	Relationship	Title	Ownership	Purchase/Sale	No. Shares	Price Per Share	Value	Shares Owned	Document Type
2025-08-01	Gillis, Steven, Crandell …	TenPercentOwner	-	Indirect	Purchase	3,030,300	3.30	$9,999,990.00	6,230,300	4
2025-08-01	Nelsen, Robert	Director,TenPercentOwner	-	Indirect	Purchase	3,030,300	3.30	$9,999,990.00	6,230,300	4
2025-08-01	Alphabet, Inc., Gv 2021, …	TenPercentOwner	-	Indirect	Purchase	1,500,000	3.30	$4,950,000.00	3,262,440	4
2025-08-01	Arch, Venture Fund Xii, L…	TenPercentOwner	-	Indirect	Purchase	3,030,300	3.30	$9,999,990.00	6,230,300	4
2025-06-30	Liu, David R.	TenPercentOwner	-	Direct	Purchase	21,000	2.52	$52,920.00	20,240,945	4
2025-06-23	Liu, David R.	TenPercentOwner	-	Direct	Purchase	21,000	2.16	$45,360.00	20,219,945	4
2025-06-16	Liu, David R.	TenPercentOwner	-	Direct	Purchase	21,000	1.49	$31,290.00	20,198,945	4
2025-06-11	Liu, David R.	TenPercentOwner	-	Direct	Purchase	21,000	1.60	$33,600.00	20,177,945	4
2025-05-21	Lee, Ann L.	Officer	Chief Technical Officer	Direct	Purchase	100,000	1.13	$113,000.00	100,000	4
2025-05-21	Reine, Allan	Director,Officer	Chief Executive Officer	Direct	Purchase	125,000	1.18	$147,500.00	125,000	4
2025-05-20	Brudnick, Richard	Officer	Chief Business Officer	Direct	Purchase	20,000	1.19	$23,800.00	20,000	4
2024-02-15	Nelsen, Robert	Director,TenPercentOwner	-	Indirect	Purchase	3,200,000	6.25	$20,000,000.00	3,200,000	4
2024-02-15	Arch, Venture Partners X,…	TenPercentOwner	-	Indirect	Purchase	3,200,000	6.25	$20,000,000.00	3,200,000	4
2024-02-15	Arch, Venture Partners Xi…	TenPercentOwner	-	Indirect	Purchase	3,200,000	6.25	$20,000,000.00	3,200,000	4
2023-06-21	Gv, 2021 Gp, L.P., Gv 201…	TenPercentOwner	-	Indirect	Sale	19,003	14.97	$284,474.91	0	4
2023-06-16	Alphabet, Inc., Gv 2021 G…	TenPercentOwner	-	Indirect	Sale	6,532	15.02	$98,110.64	0	4
2023-06-14	Gv, 2021 Gp, L.P., Gv 201…	TenPercentOwner	-	Indirect	Sale	28,960	14.87	$430,635.20	0	4
2023-06-12	Gv, 2019 Gp, L.L.C., Gv 2…	TenPercentOwner	-	Indirect	Sale	16,031	14.98	$240,144.38	0	4
2023-06-08	Gv, 2021 Gp, L.P., Alphab…	TenPercentOwner	-	Indirect	Sale	5,000	15.74	$78,700.00	0	4
2023-06-06	Gv, 2021 Gp, L.P., Gv 201…	TenPercentOwner	-	Indirect	Sale	29,975	17.02	$510,174.50	0	4
2023-06-01	Gv, 2021 Gp, L.L.C., Gv 2…	TenPercentOwner	-	Indirect	Sale	45,223	14.55	$657,994.65	0	4
2023-05-30	Gv, 2019 Gp, L.L.C., Gv 2…	TenPercentOwner	-	Indirect	Sale	16,805	13.70	$230,228.50	0	4
2023-05-25	Alphabet, Inc., Gv 2019 G…	TenPercentOwner	-	Indirect	Sale	23,161	13.38	$309,894.18	0	4
2023-05-23	Alphabet, Inc., Gv 2019, …	TenPercentOwner	-	Indirect	Sale	43,939	14.74	$647,660.86	0	4
2023-05-19	Gv, 2021 Gp, L.P., Gv 202…	TenPercentOwner	-	Indirect	Sale	63,212	13.88	$877,382.56	0	4
2023-05-17	Gv, 2021, L.P., Gv 2021 G…	TenPercentOwner	-	Indirect	Sale	15,000	12.77	$191,550.00	10,735,324	4
2023-05-15	Gv, 2019 Gp, L.L.C., Gv 2…	TenPercentOwner	-	Indirect	Sale	157,952	12.74	$2,012,308.48	10,800,973	4
2023-05-11	Gv, 2019, L.P., Alphabet …	TenPercentOwner	-	Indirect	Sale	26,626	13.38	$356,255.88	10,986,215	4
2023-05-09	Gv, 2021 Gp, L.P., Alphab…	TenPercentOwner	-	Indirect	Sale	321,238	14.08	$4,523,031.04	11,100,238	4
2022-10-24	Cahill, Thomas	Director	-	Indirect	Purchase	400,000	17.00	$6,800,000.00	5,305,679	4
2022-10-24	Nelsen, Robert	Director,TenPercentOwner	-	Indirect	Purchase	800,000	17.00	$13,600,000.00	6,128,297	4
2022-10-24	Gv, 2021, L.P., Gv 2019 G…	Other	-	Indirect	Purchase	800,000	17.00	$13,600,000.00	11,522,248	4
2022-10-24	Arch, Venture Partners X,…	TenPercentOwner	-	Indirect	Purchase	800,000	17.00	$13,600,000.00	6,128,297	4
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Institutional Ownership

No data available for chart

2026-03-31

50.86%

Inst. Shares: 90,065,815

Shares Outstanding: 177,096,225

2025-12-31

59.75%

Inst. Shares: 88,881,624

Shares Outstanding: 148,758,527

2025-09-30

50.69%

Inst. Shares: 81,351,499

Shares Outstanding: 160,503,183

2025-06-30

39.09%

Inst. Shares: 50,503,443

Shares Outstanding: 129,185,918

2025-03-31

40.55%

Inst. Shares: 53,068,112

Shares Outstanding: 130,884,490

Date	Institutional Shares Owned	Shares Outstanding	Institutional Ownership %
2026-03-31	90,065,815	177,096,225	50.86%
2025-12-31	88,881,624	148,758,527	59.75%
2025-09-30	81,351,499	160,503,183	50.69%
2025-06-30	50,503,443	129,185,918	39.09%
2025-03-31	53,068,112	130,884,490	40.55%
2024-12-31	57,285,307	118,600,381	48.30%
2024-09-30	62,008,337	119,764,270	51.78%
2024-06-30	62,360,121	119,188,866	52.32%
2024-03-31	59,372,543	104,466,178	56.83%
2023-12-31	45,352,786	90,969,327	49.86%
2023-09-30	46,787,391	91,846,835	50.94%
2023-06-30	43,552,788	90,467,298	48.14%
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Prime Medicine, Inc. (PRME) — SEC Financial Statements & Analysis

Prime Medicine, Inc. (PRME) is a biological products, (no diagnostic substances) company, incorporated in DE. Prime Medicine, Inc. trades on Nasdaq as: PRME. Based on its latest SEC filing (Form 10-Q, period ending 2026-06-30), Prime Medicine, Inc. reported a -41.16% year-over-year revenue growth, a Debt-to-Equity ratio of 5.26x, a Price-to-Sales (P/S) ratio of 224.04x (TTM), a Price-to-Book (P/B) ratio of 16.43x (TTM), at a market cap of $653.96M. Figures below are sourced from SEC EDGAR, as-filed.

Net Revenue TTM Growth 1Y: -41.16%
Debt To Equity: 5.26x
P/S TTM: 224.04x
P/B TTM: 16.43x
Market Cap: $653.96M

Data as of 2026-06-30 · Source: SEC EDGAR

Frequently Asked Questions

What industry is Prime Medicine, Inc. in?

Prime Medicine, Inc. (PRME) operates in the Biological Products, (No Diagnostic Substances) industry.

What is PRME's market cap?

Prime Medicine, Inc. (PRME) has a market capitalization of $653.96M as of 2026-06-30.

What exchange does PRME trade on?

Prime Medicine, Inc. (PRME) trades on the Nasdaq.

Where is Prime Medicine, Inc. incorporated?

Prime Medicine, Inc. is incorporated in DE.