PYXS

Pyxis Oncology, Inc.
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Company Information

Company Name
Pyxis Oncology, Inc.
CIK
CIK0001782223
Category
<br>Emerging growth company
Ticker: Exchange
PYXS: Nasdaq
Fiscal Year End
December 31
Owner Organization
03 Life Sciences
SIC
2834
SIC Description
Pharmaceutical Preparations
Ticker
PYXS

SEC filing data through

Insider Sentiment

Last purchase
2024-11-26
Last sale
2026-06-30
Shares purchased (TTM)
0
Shares sold (TTM)
35,000
Buy ratio (TTM)0.0%

Institutional Sentiment

As of
2026-06-30
Institutional shares owned
34,028,613
Shares outstanding
63,991,609
Ownership
53.18%
+9.08% Y/Y

Earnings Market Reaction

Filing date
2026-08-13
Price on filing date
—
1-month reaction
29.24%
3-month reaction
…
Drift continued6/11 (55%)
Faded / reversed5/11 (45%)

Balance Sheet

Values in millions ($)
Line item2026-06-302026-03-312025-12-312025-09-302025-06-302025-03-312024-12-312024-09-302024-06-302024-03-312023-12-312023-09-30Subscriber-only columnSubscriber-only columnSubscriber-only columnSubscriber-only columnSubscriber-only columnTrend
Assets Current
Cash And Cash Equivalents At Carrying Value1961591113191225281015
Marketable Securities Current143551677893107133131129110118
Restricted Cash Current111111111111
Accounts Receivable Net Current----3----8--
Prepaid Expense Current234575434645
Assets Current37467283100112132149161172125139
Property Plant And Equipment Net788899101011111212
Intangible Assets Net Excluding Goodwill--022332424242422
Operating Lease Right Of Use Asset11111112121212--131313
Assets556492106123136157195208220174187
Liabilities Current
Accounts Payable Current35111093555243
Accrued Liabilities Current121098710111410111317
Operating Lease Liability Current22222211-111
Contract With Customer Liability Current----------87
Liabilities Current271721191814182017142628
Operating Lease Liability Noncurrent161617171818191919202020
Finance Lease Liability Noncurrent000000000---
Liabilities433338373633364239364849
Deferred Income Tax Liabilities Net------02222-
Stockholders Equity
Common Stock Value000000000000
Additional Paid In Capital503498496494491488484481477474412409
Accumulated Other Comprehensive Income Loss Net Of Tax-0000-0000-0-00-0
Retained Earnings Accumulated Deficit-492-466-443-425-403-385-364-328-307-289-286-271
Stockholders Equity1131536988103121154170184126138
Liabilities And Stockholders Equity556492106123136157195208220174187
Preferred Stock Par Or Stated Value Per Share0.000.000.000.000.000.000.000.000.000.000.000.00
Preferred Stock Shares Authorized101010101010101010101010
Preferred Stock Shares Issued000000000000
Preferred Stock Shares Outstanding000000000000
Common Stock Par Or Stated Value Per Share0.000.000.000.000.000.000.000.000.000.000.000.00
Common Stock Shares Authorized190190190190190190190190190190190190
Common Stock Shares Issued636363626262605959594544
Shares Outstanding636363626262605959594544

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Pyxis Oncology, Inc. (PYXS) — SEC Financial Statements & Analysis

Pyxis Oncology, Inc. (PYXS) is a pharmaceutical preparations company, incorporated in DE. Pyxis Oncology, Inc. trades on Nasdaq as: PYXS. Pyxis Oncology, Inc. (PYXS)'s most recent SEC filing is a Form 10-Q for the period ended 2026-06-30, filed with the SEC on 2026-08-13. Based on that filing, Pyxis Oncology, Inc. carries a market cap of $192.61M, a P/E ratio of -2.17x, a P/B ratio of 16.84x, a P/S ratio of 17.45x, an enterprise value of $173.76M, and an EV/EBITDA multiple of -1.98x. On profitability, it posts an operating margin of -834.44%, a net margin of -803.83%, a Return on Equity (ROE) of -179.10%, a Return on Assets (ROA) of -99.62%, and a Return on Invested Capital (ROIC) of -149.68%. Per share, it reports EPS of $-1.39, diluted EPS of $-1.39, free cash flow per share of $-1.06, and a dividend per share of $0.00. Over the trailing year, it posted revenue growth of 291.42% year-over-year, net income growth of -7.85% year-over-year, and EPS growth of -10.84% year-over-year. On the balance sheet, it maintains a current ratio of 1.34x, a quick ratio of 1.25x, working capital of $9.26M, a debt-to-equity ratio of 3.80x, a debt ratio of 0.79, free cash flow of $-67.92M (TTM), and net debt of $-18.86M. Figures sourced from SEC EDGAR.

Market Cap
$192.61M
P/E TTM
-2.17x
EPS TTM
$-1.39
P/B TTM
16.84x
ROE TTM
-179.10%
ROA TTM
-99.62%
Debt To Equity
3.80x
Free Cash Flow TTM
$-67.92M
Net Revenue TTM Growth 1Y
291.42%

Data as of 2026-06-30 · Source: SEC EDGAR

Frequently Asked Questions

What industry is Pyxis Oncology, Inc. in?

Pyxis Oncology, Inc. (PYXS) operates in the Pharmaceutical Preparations industry.

What exchange does PYXS trade on?

Pyxis Oncology, Inc. (PYXS) trades on the Nasdaq.

Where is Pyxis Oncology, Inc. incorporated?

Pyxis Oncology, Inc. is incorporated in DE.

When was Pyxis Oncology, Inc. (PYXS)'s most recent SEC filing?

Pyxis Oncology, Inc. (PYXS)'s most recent SEC filing is a Form 10-Q for the period ended 2026-06-30, filed with the SEC on 2026-08-13.

What is PYXS's market cap?

Pyxis Oncology, Inc. (PYXS) has a market capitalization of $192.61M as of 2026-06-30.

What is PYXS's EPS (earnings per share)?

Pyxis Oncology, Inc. (PYXS)'s trailing twelve month EPS is $-1.39 as of 2026-06-30.

What is PYXS's ROE (return on equity)?

Pyxis Oncology, Inc. (PYXS)'s trailing twelve month Return on Equity (ROE) is -179.10% as of 2026-06-30.

What is PYXS's ROA (return on assets)?

Pyxis Oncology, Inc. (PYXS)'s trailing twelve month Return on Assets (ROA) is -99.62% as of 2026-06-30.

What is PYXS's ROIC (return on invested capital)?

Pyxis Oncology, Inc. (PYXS)'s trailing twelve month Return on Invested Capital (ROIC) is -149.68% as of 2026-03-31.

What is PYXS's EV/EBITDA?

Pyxis Oncology, Inc. (PYXS)'s trailing twelve month EV/EBITDA is -1.98x as of 2026-06-30.

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