Septerna, Inc.

SEPN

Septerna, Inc.

SEPN

Insider Sentiment (TTM):

Last Purchase:2025-03-07Last Sale:2026-06-29Shares Purchased (TTM):0Shares Sold (TTM):123,115

Institutional Sentiment:

As of:2026-03-31Institutional Shares Owned:45,555,827Shares Outstanding:44,758,800Institutional Ownership Pct.:101.78%

Earnings Market Reaction:

Filing Date:2026-08-10Price on Filing Date:N/APrevious Close:N/A% Change:N/A

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Financial Statements

10‑Q10‑K

Values in Millions ($)	2026-06-30	2026-03-31	2025-12-31	2025-09-30	2025-06-30	2025-03-31	2024-12-31	2024-09-30
Assets
Assets Current
Cash And Cash Equivalents At Carrying Value	85	72	121	320	189	210	238	88
Marketable Securities Current	288	276	270	154	137	126	113	42
Accounts Receivable Net Current	12	11	10	9	0	0	0	0
Prepaid Expense And Other Assets Current	12	10	10	9	7	6	6	3
Accounts And Other Receivables Net Current	-	-	-	-	-	-	0	-
Assets Current	396	368	411	492	334	342	357	133
Marketable Securities Noncurrent	144	175	158	87	53	62	70	7
Property Plant And Equipment Net	4	4	4	4	5	5	5	5
Operating Lease Right Of Use Asset	20	21	21	22	23	23	24	24
Restricted Cash Noncurrent	1	1	1	1	1	1	1	1
Other Assets Noncurrent	1	1	1	1	0	0	0	3
Assets	567	570	596	607	415	434	457	174
Liabilities And Stockhold…
Liabilities Current
Accounts Payable Current	4	7	10	4	7	4	3	6
Accrued Liabilities Current	13	9	12	8	7	4	8	6
Contract With Customer Liability Current	60	60	62	62	-	-	0	-
Operating Lease Liability Current	2	2	2	2	2	2	2	1
Liabilities Current	79	78	87	75	15	11	13	13
Contract With Customer Liability Noncurrent	80	92	106	121	-	-	0	-
Operating Lease Liability Noncurrent	20	21	21	22	23	23	24	24
Other Liabilities Noncurrent	1	0	0	0	0	0	0	0
Liabilities	180	191	214	218	38	34	37	38
Temporary Equity Carrying Amount Attributable To P…	-	-	-	-	-	-	-	224
Features Of Convertible P…
Stockholders Equity
Common Stock Value	0	0	0	0	0	0	0	0
Additional Paid In Capital Common Stock	577	555	549	545	542	540	538	10
Accumulated Other Comprehensive Income Loss Net Of…	-1	-1	1	0	0	0	0	0
Retained Earnings Accumulated Deficit	-189	-176	-167	-157	-165	-140	-118	-98
Stockholders Equity	387	378	382	389	378	-400	420	-87
Liabilities And Stockholders Equity	567	570	596	607	415	434	457	174
Temporary Equity Shares Authorized	-	-	0	-	-	-	0	-
Preferred Stock Par Or Stated Value Per Share	0.001	0.001	0.001	0.001	0.001	0.001	0.001	-
Preferred Stock Shares Authorized	10	10	10	10	10	10	10	-
Temporary Equity Shares Issued	-	-	0	-	-	-	0	-
Temporary Equity Shares Outstanding	-	-	0	-	-	-	0	-
Preferred Stock Shares Issued	0	0	0	0	0	0	0	-
Preferred Stock Shares Outstanding	0	0	0	0	0	0	0	-
Common Stock Par Or Stated Value Per Share	0.001	0.001	0.001	0.001	0.001	0.001	0.001	-
Common Stock Shares Authorized	500	500	500	500	500	500	500	-
Common Stock Shares Issued	46	45	45	45	45	44	44	-
Shares Outstanding	46	45	45	45	45	44	44	-

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10‑Q10‑K

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Interactive Financial Visualizations

10‑Q10‑K

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Earnings Market Reaction

10‑Q10‑K

Fiscal Year	Q1 1 Month	Q1 2 Month	Q1 3 Month	Q2 1 Month	Q2 2 Month	Q2 3 Month	Q3 1 Month	Q3 2 Month	Q3 3 Month	Q4 1 Month	Q4 2 Month	Q4 3 Month
2026	32.16%	44.25%	46.16%	-	-	-	-	-	-	-	-	-
2025	0.89%	12.35%	20.65%	25.59%	79.98%	79.29%	47.85%	54.59%	28.95%	-13.35%	-18.75%	3.92%
2024	-	-	-	-	-	-	-0.49%	-20.04%	-41.82%	-6.20%	56.44%	61.69%
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Performance and Valuation Metrics

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Metrics	2026-06-30	2026-03-31	2025-12-31	2025-09-30	2025-06-30	2025-03-31	2024-12-31	2024-09-30
Liquidity Ratios
Current Ratio	4.99	4.71	4.73	6.53	22.09	32.19	27.77	10.08
Quick Ratio	4.85	4.58	4.62	6.42	21.60	31.61	27.32	9.88
Working Capital	316.84M	289.89M	324.03M	416.40M	319.01M	331.83M	343.98M	120.18M
Leverage & Debt
Debt to Equity	0.47	0.51	0.56	0.56	0.10	-0.08	0.09	-0.43
Debt Ratio	0.32	0.34	0.36	0.36	0.09	0.08	0.08	0.22
Efficiency & Turnover
Asset Turnover TTM	0.20	0.14	0.09	0.06	0.00	-	-	-
Days Sales Outstanding TTM	22.72	28.02	41.81	71.09	39.01	-	-	-
Receivables Turnover TTM	16.06	13.03	8.73	5.13	9.36	-	-	-
Per Share Metrics
Diluted EPS TTM	-0.54	-0.81	-1.10	-1.96	-2.67	-	-	-
Free Cash Flow Per Share TTM	2.36	2.37	2.46	2.85	-2.05	-	-	-
Dividend Per Share TTM	0.00	0.00	0.00	0.00	0.00	-	-	-
Margin Metrics
Operating Profit Margin TTM	-44.04%	-77.07%	-148.63%	-486.31%	-9,604.46%	-	-	-
Net Profit Margin TTM	-24.51%	-49.88%	-106.37%	-393.35%	-8,358.95%	-	-	-
Growth Metrics
Net Revenue Growth (1Y)	6,898.02%	-	-	-	-	-	-	-
Net Income Growth (1Y)	-79.48%	-	-	-	-	-	-	-
EPS Growth (1Y)	-79.88%	-	-	-	-	-	-	-
Valuation Metrics
P/E TTM	-62.24	-29.84	-25.24	-9.33	-3.95	-	-	-
P/B TTM	3.90	2.84	3.23	2.15	1.24	-0.64	0.54	-
P/S TTM	15.25	14.89	26.85	36.69	330.38	-	-	-
Market Cap	1.51B	1.08B	1.23B	834.09M	466.83M	254.40M	226.51M	-
Enterprise Value	1.42B	1.00B	1.11B	514.10M	277.51M	44.35M	-11.69M	-
Calculated Values
Free Cash Flow TTM	106.17M	106.28M	109.02M	126.23M	-90.57M	-	-	-
Net Debt	-84.66M	-71.61M	-120.72M	-319.99M	-189.31M	-210.05M	-238.20M	-88.24M
Per-Share and Margin
EPS TTM
Adjusted EPS TTM
Cash Flow Per Share TTM
Pretax Margin TTM
Stock Comp to Revenue TTM
Turnover Ratios and Averages
Average Assets
Average Equity
Average Inventory
Average Receivables
Average Accounts Payables
Inventory Turnover TTM
Payables Turnover TTM
Days Inventory Outstanding TTM
Days Payables Outstanding TTM
Cash Conversion Cycle TTM
Working Capital to Revenue
Deferred Revenue to Revenue
Growth Rates
Total Assets Growth (1Y)
Total Assets Growth (3Y)
Total Assets Growth (5Y)
Dividends Paid Growth (1Y)
Dividends Paid Growth (3Y)
Dividends Paid Growth (5Y)
EPS Growth (3Y)
EPS Growth (5Y)
Net Income Growth (3Y)
Net Income Growth (5Y)
Net Profit Margin Growth (1Y)
Net Profit Margin Growth (3Y)
Net Profit Margin Growth (5Y)
Net Revenue Growth (3Y)
Net Revenue Growth (5Y)
Deferred Revenue Growth (1Y)
Retained Earnings Growth (1Y)
Credit, Liquidity, Returns, Payout
Cash Ratio
Net Working Capital
Debt to EBITDA TTM
Net Debt to EBITDA TTM
Net Debt to Equity
Altman A
Altman B
Altman C
Altman D
Altman E
Altman Z-Score
ROA TTM
ROE TTM
NOPAT TTM
ROIC TTM
Effective Tax Rate TTM
Payout Ratio TTM
Dilution Ratio
Retained Earnings to Equity
Treasury Stock to Equity
Treasury Stock Change (1Y)
Accrued to Current Liabilities
NCAV
NCAV Per Share TTM
Valuation Ratios
P/CF TTM
PEG Ratio
Dividend Yield TTM
Free Cash Flow Yield TTM
EV EBITDA TTM
EV EBIT TTM
EV Revenue TTM
EV FCF TTM
Stock Compensation TTM
Adjusted Net Income TTM
Billings TTM
Total Debt
Invested Capital

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Insider Transactions

2026-06-29Sale

Owner: Shaikhly, Samira

Title: Chief People Officer

Shares: 2,178

Price/Share: $35.18

Value: $76,622.04

Shares Owned: 793

Relationship: Officer

Ownership: Direct

2026-06-22Sale

Owner: Long, Daniel D.

Title: SVP, Drug Discovery

Shares: 15,000

Price/Share: $35.53

Value: $532,950.00

Shares Owned: 96,412

Relationship: Officer

Ownership: Direct

2026-06-12Sale

Owner: Shaikhly, Samira

Title: Chief People Officer

Shares: 6,250

Price/Share: $35.08

Value: $219,250.00

Shares Owned: 793

Relationship: Officer

Ownership: Direct

2026-06-01Sale

Owner: Shaikhly, Samira

Title: Chief People Officer

Shares: 5,935

Price/Share: $28.74

Value: $170,571.90

Shares Owned: 793

Relationship: Officer

Ownership: Direct

2026-05-26Sale

Owner: Shaikhly, Samira

Title: Chief People Officer

Shares: 11,798

Price/Share: $30.06

Value: $354,647.88

Shares Owned: 793

Relationship: Officer

Ownership: Direct

Filed Date	Owner	Relationship	Title	Ownership	Purchase/Sale	No. Shares	Price Per Share	Value	Shares Owned	Document Type
2026-06-29	Shaikhly, Samira	Officer	Chief People Officer	Direct	Sale	2,178	35.18	$76,622.04	793	4
2026-06-22	Long, Daniel D.	Officer	SVP, Drug Discovery	Direct	Sale	15,000	35.53	$532,950.00	96,412	4
2026-06-12	Shaikhly, Samira	Officer	Chief People Officer	Direct	Sale	6,250	35.08	$219,250.00	793	4
2026-06-01	Shaikhly, Samira	Officer	Chief People Officer	Direct	Sale	5,935	28.74	$170,571.90	793	4
2026-05-26	Shaikhly, Samira	Officer	Chief People Officer	Direct	Sale	11,798	30.06	$354,647.88	793	4
2026-04-15	Bhatt, Elizabeth	Officer	President and COO	Direct	Sale	4,000	24.95	$99,800.00	174,209	4
2026-03-02	Shaikhly, Samira	Officer	Chief People Officer	Direct	Sale	70,453	27.83	$1,960,706.99	793	4
2026-02-18	Bhatt, Elizabeth	Officer	President and COO	Direct	Sale	4,000	29.02	$116,080.00	174,209	4
2025-11-10	Long, Daniel D.	Officer	SVP, Drug Discovery	Direct	Sale	3,501	18.06	$63,228.06	92,911	4
2025-03-07	Ezekowitz, Alan	Director	-	Direct	Purchase	13,319	6.93	$92,300.67	117,420	4
2025-03-06	Ezekowitz, Alan	Director	-	Direct	Purchase	41,355	6.00	$248,130.00	104,101	4
2025-02-27	Finer, Jeffrey	Director,Officer	CEO and President	Direct	Purchase	3,000	5.80	$17,400.00	771,907	4
2025-02-27	Labrucherie, Gil M	Officer	Chief Financial Officer	Indirect	Purchase	3,718	5.85	$21,750.30	40,000	4
2025-02-24	Third, Rock Ventures Gp V…	TenPercentOwner	-	Direct	Purchase	18,861	6.00	$113,166.00	4,211,659	4
2025-02-21	Labrucherie, Gil M	Officer	Chief Financial Officer	Indirect	Purchase	5,000	5.85	$29,250.00	30,000	4
2025-02-21	Third, Rock Ventures Gp V…	TenPercentOwner	-	Direct	Purchase	427,668	5.94	$2,540,347.92	4,192,798	4
2024-10-28	Trv, Gp V, Llc, Third Roc…	TenPercentOwner	-	Direct	Purchase	370,500	18.00	$6,669,000.00	6,215,591	4
2024-10-28	Shah, Rajeev M., Ra Capit…	Director,TenPercentOwner	-	Indirect	Purchase	4,170,000	18.00	$75,060,000.00	5,523,915	4
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Institutional Ownership

No data available for chart

2026-03-31

101.78%

Inst. Shares: 45,555,827

Shares Outstanding: 44,758,800

2025-12-31

102.75%

Inst. Shares: 45,474,229

Shares Outstanding: 44,258,338

2025-09-30

100.39%

Inst. Shares: 44,516,504

Shares Outstanding: 44,343,085

2025-06-30

100.30%

Inst. Shares: 44,299,338

Shares Outstanding: 44,165,168

2025-03-31

102.88%

Inst. Shares: 45,203,761

Shares Outstanding: 43,937,410

Date	Institutional Shares Owned	Shares Outstanding	Institutional Ownership %
2026-03-31	45,555,827	44,758,800	101.78%
2025-12-31	45,474,229	44,258,338	102.75%
2025-09-30	44,516,504	44,343,085	100.39%
2025-06-30	44,299,338	44,165,168	100.30%
2025-03-31	45,203,761	43,937,410	102.88%
2024-12-31	43,560,813	9,891,126	-
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Septerna, Inc. (SEPN) — SEC Financial Statements & Analysis

Septerna, Inc. (SEPN) is a pharmaceutical preparations company, incorporated in DE. Septerna, Inc. trades on Nasdaq as: SEPN. Based on its latest SEC filing (Form 10-Q, period ending 2026-06-30), Septerna, Inc. reported a 6898.02% year-over-year revenue growth, a Debt-to-Equity ratio of 0.47x, a Price-to-Sales (P/S) ratio of 15.25x (TTM), a Price-to-Book (P/B) ratio of 3.90x (TTM), at a market cap of $1.51B. Figures below are sourced from SEC EDGAR, as-filed.

Net Revenue TTM Growth 1Y: 6898.02%
Debt To Equity: 0.47x
P/S TTM: 15.25x
P/B TTM: 3.90x
Market Cap: $1.51B

Data as of 2026-06-30 · Source: SEC EDGAR

Frequently Asked Questions

What industry is Septerna, Inc. in?

Septerna, Inc. (SEPN) operates in the Pharmaceutical Preparations industry.

What is SEPN's market cap?

Septerna, Inc. (SEPN) has a market capitalization of $1.51B as of 2026-06-30.

What exchange does SEPN trade on?

Septerna, Inc. (SEPN) trades on the Nasdaq.

Where is Septerna, Inc. incorporated?

Septerna, Inc. is incorporated in DE.

Septerna, Inc.

Financial Statements

Custom Table

Interactive Financial Visualizations

Earnings Market Reaction

Performance and Valuation Metrics

Insider Transactions

Institutional Ownership

Septerna, Inc. (SEPN) — SEC Financial Statements & Analysis

Frequently Asked Questions

Companies in Pharmaceutical Preparations

Wall Street's data.
Main Street's price.

Septerna, Inc. (SEPN) — SEC Financial Statements & Analysis

Frequently Asked Questions

Companies in Pharmaceutical Preparations

Wall Street's data.Main Street's price.

Wall Street's data.
Main Street's price.