SPRO

Spero Therapeutics, Inc.
—

Company Information

Company Name
Spero Therapeutics, Inc.
CIK
CIK0001701108
Category
Non-accelerated filer<br>Smaller reporting company
Ticker: Exchange
SPRO: Nasdaq
Fiscal Year End
December 31
Owner Organization
03 Life Sciences
SIC
2834
SIC Description
Pharmaceutical Preparations
Ticker
SPRO

SEC filing data through

Insider Sentiment

Last purchase
—
Last sale
2026-05-04
Shares purchased (TTM)
0
Shares sold (TTM)
202,259
Buy ratio (TTM)0.0%

Institutional Sentiment

As of
2026-06-30
Institutional shares owned
21,177,166
Shares outstanding
57,968,608
Ownership
36.53%
+17.01% Y/Y

Earnings Market Reaction

Filing date
2026-08-12
Price on filing date
—
1-month reaction
1.68%
3-month reaction
…
Drift continued6/11 (55%)
Faded / reversed5/11 (45%)

Balance Sheet

Values in millions ($)
Line item2026-06-302026-03-312025-12-312025-09-302025-06-302025-03-312024-12-312024-09-302024-06-302024-03-312023-12-312023-09-30Subscriber-only columnSubscriber-only columnSubscriber-only columnSubscriber-only columnSubscriber-only columnTrend
Assets Current
Cash And Cash Equivalents At Carrying Value515640493149537664827694
Other Assets Current000221335523
Prepaid Expense And Other Assets Current112112223445
Assets Current525867525975107132122140131102
Operating Lease Right Of Use Asset111233334444
Property Plant And Equipment Net------000000
Other Assets Noncurrent000000000000
Assets535969546278111135150168182107
Liabilities Current
Accounts Payable Current001112763311
Operating Lease Liability Current222222222222
Taxes Payable Current000000000002
Deferred Revenue Current--00000143214
Liabilities Current859141529494946423725
Operating Lease Liability Noncurrent011122333444
Deferred Revenue Noncurrent--013131312129101124
Other Long Term Debt Noncurrent000---000000
Liabilities9610282944647069717553
Stockholders Equity Including Portion Attributable To Noncontrolling Interest
Preferred Stock Value000000000000
Common Stock Value000000000000
Additional Paid In Capital Common Stock512511510509508507506504502500498496
Retained Earnings Accumulated Deficit-468-458-451-483-475-474-460-439-422-404-391-442
Stockholders Equity4453592633344666819610754
Accumulated Other Comprehensive Income Loss Net Of Tax----------00
Liabilities And Stockholders Equity535969546278111135150168182107
Preferred Stock Par Or Stated Value Per Share0.000.000.000.000.000.000.000.000.000.000.000.00
Preferred Stock Shares Authorized101010101010101010101010
Preferred Stock Shares Issued000000000000
Preferred Stock Shares Outstanding000000000000
Common Stock Par Or Stated Value Per Share0.000.000.000.000.000.000.000.000.000.000.000.00
Common Stock Shares Authorized240120120120120120120120120120120120
Common Stock Shares Issued585856565656555454545353
Shares Outstanding585856565656555454545353

Select a line item above to chart it.

Recent filings

Financial statements beyond 3 years are for subscribers only.

Unlock 17+ years of income statements, balance sheets, and cash flow statements

Start 7-day free trial

Spero Therapeutics, Inc. (SPRO) — SEC Financial Statements & Analysis

Spero Therapeutics, Inc. (SPRO) is a pharmaceutical preparations company, incorporated in DE. Spero Therapeutics, Inc. trades on Nasdaq as: SPRO. Spero Therapeutics, Inc. (SPRO)'s most recent SEC filing is a Form 10-Q for the period ended 2026-06-30, filed with the SEC on 2026-08-12. Based on that filing, Spero Therapeutics, Inc. carries a market cap of $128.11M, a P/E ratio of 17.35x, a P/B ratio of 2.90x, a P/S ratio of 9.98x, an enterprise value of $77.34M, and an EV/EBITDA multiple of 12.84x. On profitability, it posts an operating margin of 46.95%, a net margin of 57.54%, a Return on Equity (ROE) of 19.17%, a Return on Assets (ROA) of 12.85%, and a Return on Invested Capital (ROIC) of 103.09%. Per share, it reports EPS of $0.13, diluted EPS of $0.13, free cash flow per share of $0.34, and a dividend per share of $0.00. Over the trailing year, it posted revenue growth of 9847.29% year-over-year, net income growth of -113.77% year-over-year, and EPS growth of -113.31% year-over-year. On the balance sheet, it maintains a current ratio of 6.12x, a quick ratio of 6.03x, working capital of $43.16M, a debt-to-equity ratio of 0.19x, a debt ratio of 0.16, free cash flow of $19.58M (TTM), and net debt of $-50.77M. Figures sourced from SEC EDGAR.

Market Cap
$128.11M
P/E TTM
17.35x
EPS TTM
$0.13
P/B TTM
2.90x
ROE TTM
19.17%
ROA TTM
12.85%
Debt To Equity
0.19x
Free Cash Flow TTM
$19.58M
Net Revenue TTM Growth 1Y
9847.29%

Data as of 2026-06-30 · Source: SEC EDGAR

Frequently Asked Questions

What industry is Spero Therapeutics, Inc. in?

Spero Therapeutics, Inc. (SPRO) operates in the Pharmaceutical Preparations industry.

What exchange does SPRO trade on?

Spero Therapeutics, Inc. (SPRO) trades on the Nasdaq.

Where is Spero Therapeutics, Inc. incorporated?

Spero Therapeutics, Inc. is incorporated in DE.

When was Spero Therapeutics, Inc. (SPRO)'s most recent SEC filing?

Spero Therapeutics, Inc. (SPRO)'s most recent SEC filing is a Form 10-Q for the period ended 2026-06-30, filed with the SEC on 2026-08-12.

What is SPRO's market cap?

Spero Therapeutics, Inc. (SPRO) has a market capitalization of $128.11M as of 2026-06-30.

What is SPRO's P/E ratio?

Spero Therapeutics, Inc. (SPRO)'s trailing twelve month P/E ratio is 17.35x as of 2026-06-30.

What is SPRO's EPS (earnings per share)?

Spero Therapeutics, Inc. (SPRO)'s trailing twelve month EPS is $0.13 as of 2026-06-30.

What is SPRO's ROE (return on equity)?

Spero Therapeutics, Inc. (SPRO)'s trailing twelve month Return on Equity (ROE) is 19.17% as of 2026-06-30.

What is SPRO's ROA (return on assets)?

Spero Therapeutics, Inc. (SPRO)'s trailing twelve month Return on Assets (ROA) is 12.85% as of 2026-06-30.

What is SPRO's ROIC (return on invested capital)?

Spero Therapeutics, Inc. (SPRO)'s trailing twelve month Return on Invested Capital (ROIC) is 103.09% as of 2025-12-31.

What is SPRO's EV/EBITDA?

Spero Therapeutics, Inc. (SPRO)'s trailing twelve month EV/EBITDA is 12.84x as of 2026-06-30.

Wall Street's data.
Main Street's price.