Upstream Bio, Inc.
Upstream Bio, Inc.
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Financial Statements
Values in Millions ($) | 2026-06-30 | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | Subscriber-only column | Subscriber-only column | Subscriber-only column | Subscriber-only column | Financial statements beyond 3 years are for subscribers only. Unlock 17+ years of income statements, balance sheets, and cash flow statements Start 7-day free trial |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Series A And B Redeemable Convertible Preferred St… | - | - | - | - | - | - | - | 0 | |||||
Assets | |||||||||||||
Assets Current | |||||||||||||
Cash And Cash Equivalents At Carrying Value | 79 | 97 | 102 | 72 | 45 | 71 | 326 | 33 | |||||
Short Term Investments | 182 | 198 | 240 | 300 | 348 | 360 | 145 | 188 | |||||
Accounts Receivable Net Current | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | |||||
Prepaid Expense And Other Assets Current | 18 | 21 | 10 | 16 | 24 | 22 | 8 | 6 | |||||
Assets Current | 280 | 316 | 352 | 389 | 418 | 454 | 479 | 227 | |||||
Property Plant And Equipment Net | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | |||||
Operating Lease Right Of Use Asset | 1 | 1 | 1 | 1 | 2 | 2 | 2 | 2 | |||||
Restricted Cash Noncurrent | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||||
Assets | 281 | 318 | 354 | 391 | 421 | 456 | 482 | 233 | |||||
Liabilities And Stockhold… | |||||||||||||
Liabilities Current | |||||||||||||
Accounts Payable Current | 2 | 2 | 3 | 4 | 3 | 5 | 4 | 5 | |||||
Accrued Liabilities And Other Liabilities | 7 | 11 | 10 | 7 | 8 | 4 | 6 | 5 | |||||
Operating Lease Liability Current | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | |||||
Liabilities Current | 10 | 14 | 13 | 12 | 11 | 10 | 11 | 11 | |||||
Operating Lease Liability Noncurrent | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | |||||
Liabilities | 10 | 14 | 14 | 13 | 12 | 11 | 12 | 12 | |||||
Stockholders Equity | |||||||||||||
Temporary Equity Carrying Amount Attributable To P… | - | - | - | - | - | - | 0 | 381 | |||||
Common Stock Value | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||||
Additional Paid In Capital | 686 | 679 | 673 | 670 | 666 | 663 | 661 | 9 | |||||
Accumulated Other Comprehensive Income Loss Net Of… | -0 | 0 | 1 | 0 | 0 | 0 | -0 | 0 | |||||
Retained Earnings Accumulated Deficit | -415 | -375 | -334 | -292 | -258 | -218 | -191 | -170 | |||||
Stockholders Equity | 271 | 304 | 340 | 379 | 409 | 446 | 470 | -160 | |||||
Liabilities And Stockholders Equity | 281 | 318 | 354 | 391 | 421 | 456 | 482 | 233 | |||||
Temporary Equity Shares Authorized | - | - | - | - | - | - | - | 32 | |||||
Temporary Equity Shares Issued | - | - | - | - | - | - | - | 32 | |||||
Temporary Equity Shares Outstanding | - | - | - | - | - | - | - | 32 | |||||
Temporary Equity Liquidation Preference | - | - | - | - | - | - | - | 431 | |||||
Preferred Stock Par Or Stated Value Per Share | 0.001 | 0.001 | 0.001 | 0.001 | 0.001 | 0.001 | 0.001 | - | |||||
Preferred Stock Shares Authorized | 10 | 10 | 10 | 10 | 10 | 10 | 10 | - | |||||
Preferred Stock Shares Issued | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - | |||||
Preferred Stock Shares Outstanding | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - | |||||
Common Stock Par Or Stated Value Per Share | 0.001 | 0.001 | 0.001 | 0.001 | 0.001 | 0.001 | 0.001 | 0.001 | |||||
Common Stock Shares Authorized | 500 | 500 | 500 | 500 | 500 | 500 | 500 | 41 | |||||
Common Stock Shares Issued | 55 | 54 | 54 | 54 | 54 | 54 | 54 | 3 | |||||
Shares Outstanding | 55 | 54 | 54 | 54 | 54 | 54 | 54 | 3 | |||||
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Earnings Market Reaction
| Fiscal Year | Q1 1 Month | Q1 2 Month | Q1 3 Month | Q2 1 Month | Q2 2 Month | Q2 3 Month | Q3 1 Month | Q3 2 Month | Q3 3 Month | Q4 1 Month | Q4 2 Month | Q4 3 Month |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | -24.68% | -19.76% | -29.81% | - | - | - | - | - | - | - | - | - |
| 2025 | 12.42% | 33.13% | 66.02% | 2.45% | 3.23% | 30.74% | 19.32% | 22.99% | 25.24% | 2.04% | -7.15% | -37.69% |
| 2024 | - | - | - | - | - | - | -19.06% | -28.98% | -61.55% | -33.91% | -6.39% | 0.00% |
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Performance and Valuation Metrics
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Insider Transactions
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Institutional Ownership
Upstream Bio, Inc. (UPB) — SEC Financial Statements & Analysis
Upstream Bio, Inc. (UPB) is a pharmaceutical preparations company, incorporated in DE. Upstream Bio, Inc. trades on Nasdaq as: UPB. Based on its latest SEC filing (Form 10-Q, period ending 2026-06-30), Upstream Bio, Inc. reported a -18.46% year-over-year revenue growth, a Debt-to-Equity ratio of 0.04x, a Price-to-Sales (P/S) ratio of 119.57x (TTM), a Price-to-Book (P/B) ratio of 1.39x (TTM), at a market cap of $377.61M. Figures below are sourced from SEC EDGAR, as-filed.
- Net Revenue TTM Growth 1Y
- -18.46%
- Debt To Equity
- 0.04x
- P/S TTM
- 119.57x
- P/B TTM
- 1.39x
- Market Cap
- $377.61M
Data as of 2026-06-30 · Source: SEC EDGAR
Frequently Asked Questions
What industry is Upstream Bio, Inc. in?
Upstream Bio, Inc. (UPB) operates in the Pharmaceutical Preparations industry.
What is UPB's market cap?
Upstream Bio, Inc. (UPB) has a market capitalization of $377.61M as of 2026-06-30.
What exchange does UPB trade on?
Upstream Bio, Inc. (UPB) trades on the Nasdaq.
Where is Upstream Bio, Inc. incorporated?
Upstream Bio, Inc. is incorporated in DE.